November 4, 2013

November 4, 2013

New Ways to Beat Gonorrhea

Welcome to another day in my life. Today is Monday and I hope you had a beary safe and great weekend. It was another busy weekend for the Dab Bears and me.

The Centers for Disease Control and Prevention (CDC) and the National Institutes of Health (NIH) have announced that two new antibiotic regimens are highly effective at treating gonorrhea. The sexually transmitted infection (STI) has developed resistance to nearly all the current arsenal of treatments. Participants in the clinical trials of the new antibiotics reported significant side effects, most notably gastrointestinal problems, so the CDC is not currently changing its treatment guidelines for the STI.

Gonorrhea and other STIs facilitate the spread of HIV by increasing viral load and by increasing the presence of cells that HIV targets.

In a Phase IV clinical trial, a combo of injectable gentamicin and oral azithromycin was 100 percent effective at curbing gonorrhea, and oral gemifloxacin with azithromycin was 99.5 percent effective.

Of those taking the first combo, 28 percent experienced nausea, 19 percent diarrhea and 7 percent either abdominal discomfort or vomiting. Of those taking the latter combo, 37 percent experienced nausea, 23 percent diarrhea and 11 percent abdominal discomfort.

Robert Kirkcaldy, MD, MPH, a medical epidemiologist at the CDCís Division of STD Prevention, says that while the new drug options ďdo provide some hope against drug-resistant gonorrhea, they really donít address the urgent needs for additional first-line treatments that are safe and well-tolerated.Ē The CDC and NIH are working to find new solutions and are encouraging further research.

Now of course the best way to avoid infection is to use a condom every time regardless of whether you're having vaginal or anal sex.

Hope you have a beary safe and great Monday!

Until we meet again; here's wishing you health, hope, happiness and just enough.

big bear hug,

Daddy Dab